Nefazodone Hydrochloride
Nefazodone HCL
CAS: 82752-99-6
Molecular Formula: C25H33Cl2N5O2
Nefazodone Hydrochloride - Names and Identifiers
| Name | Nefazodone HCL |
| Synonyms | NEFAZODONE Nefazodone HCL Nefazodone HCl NEFAZODONE-D5 HCL Nefazodone hydrochloride Nefazodone Hydrochloride Nefazodone Hydrochloride (200 mg) 2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride 3H-1,2,4-Triazol-3-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride BMY-13754, MJ-13754-1, Serzone, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride |
| CAS | 82752-99-6 |
| InChI | InChI=1/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H |
Nefazodone Hydrochloride - Physico-chemical Properties
| Molecular Formula | C25H33Cl2N5O2 |
| Molar Mass | 506.47 |
| Melting Point | 186-188°C |
| Boling Point | 599.6°C at 760 mmHg |
| Flash Point | 316.4°C |
| Solubility | DMSO: ~11mg/mL at60°C |
| Vapor Presure | 2.46E-14mmHg at 25°C |
| Appearance | solid |
| Color | white |
| Maximum wavelength(λmax) | 248nm(MeOH)(lit.) |
| Merck | 14,6438 |
| Storage Condition | Inert atmosphere,Room Temperature |
| In vitro study | Nefazodone hydrochloride (BMY-13754) is a phenylpiperazine antidepressant with a mechanism of action that is distinct from those of other currently available drugs. Nefazodone hydrochloride potently and selectively blocks postsynaptic serotonin (5-hydroxytryptamine; 5-HT) 5-HT2A receptors and moderately inhibits serotonin and noradrenaline (norepinephrine) reuptake. Nefazodone hydrochloride is also an inhibitor of the hepatic P-450 isoenzyme CYP3A4. |
Nefazodone Hydrochloride - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| RTECS | XZ5483009 |
| HS Code | 2933595960 |
Nefazodone Hydrochloride - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.974 ml | 9.872 ml | 19.745 ml |
| 5 mM | 0.395 ml | 1.974 ml | 3.949 ml |
| 10 mM | 0.197 ml | 0.987 ml | 1.974 ml |
| 5 mM | 0.039 ml | 0.197 ml | 0.395 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Nefazodone Hydrochloride Visit Supplier Webpage Request for quotationCAS: 82752-99-6
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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Product Name: Nefazodone Hydrochloride Visit Supplier Webpage Request for quotationCAS: 82752-99-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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